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Author: search.filters.author.Genchi,GiuseppeHas files: Yes

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    Effetto dell'acido retinoico sulle cellule del leydig: regolazione dell'apoptosi e della steroidogenesi
    (2013-06-14) Tucci,Paola; Bagetta,Giacinto; Genchi,Giuseppe
    In addition to playing a foundamental role in very diverse processes such as vision and growth and differentiation, vitamin A (retinol) and its main biologically active derivate, retinoic acid (RA), are clearly involved in the regulation of testicular functions. Indeed vitamin A is necessary for the normal development and function of rodent testis. Accordingly, vitamin A deficiency results in testicular edema, degeneration of germinal epithelium and cessation of spermatogenesis.